Localization of Deoxyribonucleic Acid Complementary to Ribosomal Ribonucleic Acid and Preribosomal Ribonucleic Acid in the Nucleolus of Rat Liver

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Localization of deoxyribonucleic acid complementary to ribosomal ribonucleic acid and preribosomal ribonucleic acid in the nucleolus of rat liver.

The fraction and distribution of DNA complementary to ribosomal RNA and preribosomal RNA was investigated by the technique of molecular hybridization with the DNA of isolated nucleoli and nuclei of rat liver. Nuclear DNA complementary to ribosomal 18 S RNA and 28 S RNA was 0.014% and 0.032%, respectively. Nucleolar DNA complementary to ribosomal 18 S RNA and 28 S RNA was 0.10% and 0.22%, respec...

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The Enzymatic Methylation of Ribonucleic Acid and Deoxyribonucleic Acid. Vii. the Methylation of Ribonucleic Acid.

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Enzymatic Synthesis of Ribonucleic Acid. Iv. the Deoxyribonucleic Acid-directed Synthesis of Complementary Cytoplasmic Ribonucleic Acid Components.

The ribonucleic acid product formed by ribonucleic acid polymerase resembles its deoxyribonucleic acid template in base composition and in base sequence (l-6). The reaction in vitro results in the synthesis of RNA chains which are complementary to both DNA strands (6). Evidence for this originates from the formation of highly ordered RNA structures when the RNA polymerase product is annealed wi...

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The Enzymatic Phosphorylation of Ribonucleic Acid and Deoxyribonucleic Acid

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Ribonucleic Acid Composition of Rat Liver Tumor

Studies on normal tissues have suggested that the ribonucleic acid (RNA) of nuclei, mitochon dna, microsomes, and supernatant fluid isolated from tissue homogenate has a characteristic nu cleotide composition (7, 8, 16), while other data did not support such a view (6). Results obtained in this laboratory revealed, in fact, the occurrence of characteristic ribonucleic acids in rat liver frac ti...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1968

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)93311-9